Dextrose Type Solution

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  • Dextrose is required for maintaining an osmotic gradient between the blood and dialysate. Hemodialysis against a dextrose free dialysate results in a net loss of glucose approximately 1 gm per litre fully equilibrated dialysate, or 24 to 36 gm per day during CRRT.
  • Patients on CRRT with a glucose free dialysate could be at risk if no additional glucose support such as dextrose in water by intravenous or total parenteral nutrition(TPN) or oral feeds was provided.

The composition of the dialysis solution is as follows:

PART I : The acid concentrate (in liquid form) is composed of the following components in each 1000ml:

  • NaCl : 208.8g
  • KCl: 5.50g
  • CaCl2: 8.10g
  • MgCl2: 3.75g
  • Dextrose monohydrate: NA
  • CH3COOH: 6.86g
  • H20: Q.S

PART II: The bicarb concentrate part containing

  • NaHCO3: 558g

Procedure for use:

  • Part I supplied in liquid form in white jerry cans of 10 lts.
  • Part II supplied in polythene bags of 900 g each (2 packs are supplied with each can)
  • The total contents of part II are dissolved in purified water up to 10lts
  • The operator manual of the individual dialysis machine should be followed to obtain the final dialysate options based on a compatible concentrate-pair and standard proportioning ratio to give a final solution by mixing 1:1.83:34 parts of part I:part II: purified water.